Compile Data Set for Download or QSAR
Found 3 of ec50 data for polymerid = 5421
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309182(4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26974J2PubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309178(4-(2-Amino-5-(benzo[d][1,3]dioxol-4-yl)pyridin-3-y...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair